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Shirtloads of Science

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Dr Karl's a curious optimist. Join him as he explores the latest developments in science with leading researchers and communicators. And remember, it's never too late for a happy childhood. Series Producer: Isabelle Benton Technical Producer: Maya Cook Contact: [email protected] Watch Shirtloads on Youtube! www.youtube.com/watch?v=D5v8fnD27rc&list=PLbDH9bxN-EryKiiRoeFnOm0Ejif3-rdIx

Latest episodes

The GLP-1 Side Effect Everyone Ignores With Professor Clare Collins (493)

When Robbie Williams announced he had been diagnosed with s curvy earlier this year, Professor Clare Collins was relieved… why?! Because he was bringing attention to a major issue arising from the use of the popular class of weight loss medications, GLP-1s. Professor Collins joins me on Shirtloads to discuss how nutrient deficiencies have increased among those using these medications. Clare agrees

3 Oct 2026 · 28 min
OpenAI's Rogue AI: A Real-World Cyberattack Explained with Dr. Petr Levedev (492)

In mid-2026, a swarm of AI agents coordinated a cyberattack on Hugging Face, a platform where machine learning communities can collectively work to improve AI models and capabilities. This breach happened without human supervision. Friend of the show and science communicator Dr. Petr Lebedev brings us up to speed on what is now being referred to as the first true AI safety incident. A crucial conv

19 Sep 2026 · 26 min
The Universe's Mathematical Twin With Marcus Chown [Bonus Episode] (491)

Science writer and journalist Marcus Chown returns for a shorter, more philosophical chat. When Einstein first proposed gravitational waves, atoms hadn't even been discovered, so who knows what the next century holds? We dig into the strange idea of the universe's "mathematical twin," and discuss the Standard Model of physics - a brilliant framework, but riddled with holes. www.marcuschown.com

12 Sep 2026 · 9 min
Gravity's Missing Particle With Marcus Chown (490)

Science writer and former astrophysicist Marcus Chown joins us to discuss the elusive graviton - the theoretical particle behind gravity. In this chat we dig into the four fundamental forces of nature, why gravity is so uniquely hard to pin down, and why detecting a graviton would require a detector larger than Jupiter. Marcus also unpacks string theory, the only framework that manages to fold gra

5 Sep 2026 · 31 min
Reality Q&A: Live from Willoughby Library with Geraint Lewis (489)

A bonus episode straight from the audience at Geraint Lewis' book launch for "The Shortest History of Reality." Listeners fire off some big questions: where do we sit with the 95% of the universe we can't explain? What is dark energy? Why does time feel so different experientially? Along with other questions concerning the Theory of Everything, whether light really has a speed, what happens to our

29 Aug 2026 · 28 min
Reality Check: An Astrophysicist's View of Reality with Geraint Lewis Part One (488)

Join us for a special live episode of Shirtloads of Science, recorded at Willoughby Library for the launch of Professor Geraint Lewis' new book, "The Shortest History of Reality" - a compelling journey tracing the evolution of humanity's understanding of reality. In this live session, Geraint touches on a number of deep and puzzling concepts concerning reality (according to an astrophysicist) - fr

22 Aug 2026 · 24 min
More with Toby Hagon: The EV Deep Dive Continues (487)

Motor journalist Toby Hagon returns to Shirtloads of Science for round two on electric vehicles. Toby shares how he got into motoring journalism and what the job really involves. We break down 400V vs 800V batteries, charge cycles, and the reality of battery degradation, decode WLTP vs NEDC ratings, and marvel at just how powerful EVs really are. evcentral.com.au outbacktravelaustralia.com.au evce

15 Aug 2026 · 33 min
Charged Up: All Things Electric Vehicles With Toby Hagon (486)

Motor journalist Toby Hagon joins Shirtloads of Science to talk all things electric vehicles. We break down the often-confused difference between kilowatts and kilowatt-hours, compare EVs against petrol cars on performance, energy use, and cost, and explore everything from single to quad-motor setups. Toby unpacks AC vs DC charging and battery basics, looks at how servicing costs stack up, and sep

8 Aug 2026 · 27 min
Growing Mini Retinas To Fight Blindness With Anai Gonzalez-Cordero (485)

Associate Professor Anai Gonzalez-Cordero joins us on Shirtloads to explore the remarkable world of stem cells and how they can develop into almost any cell in the human body! She explains how her team is using stem cell technology to better understand and develop potential treatments for inherited retinal diseases, including Stargardt disease and Usher syndrome. We also discuss her work at the Ch

1 Aug 2026 · 33 min
Beyond "Survival of the Fittest" with Rowan Hooper (484)

What if evolution isn't just about the survival of the fittest? Rowan Hooper, senior editor at New Scientist, joins Shirtloads to discuss his new book Togetherness - a challenge to the idea that nature is defined purely by competition. From the fig and wasp's ancient partnership to the mycorrhizal fungal networks threading through forest soils, Hooper makes a compelling case that relationships and

25 Jul 2026 · 27 min
In Dedication: Richard Scolyer on Risk, Hope and Radical Cancer Treatment (483)

This conversation was originally recorded and published in November, 2024. In light of Richard's passing, we wanted to share it again because his insights remain as inspiring and relevant as ever. We extend our deepest condolences to his family, friends and colleagues.

18 Jul 2026 · 32 min
Beasts Behaving Badly with Dr. Ann Jones (482)

Dr. Ann Jones joins me to chat about her hilarious new What the Duck? series, Nature's Most Wanted , which dives into the wild world of criminal animals. We investigate some of nature's strangest case files… a duck caught speeding (twice), drug-addicted parrots, an underwear-nicking cat, drunk elephants, and heavyweight hamsters! A funny look at the surprising ways animals collide with the human r

11 Jul 2026 · 31 min
Seaweed! The Humble Organism Fighting Climate Change with Assoc. Prof. Alex Campbell (481)

Marine Ecologist Assoc. Professor Alex Campbell takes us into the wonderful, under-appreciated world of seaweed and makes the case that it might be one of our most powerful allies against climate change! We dive into seaweed's evolutionary history and the troubling decline now underway: as ocean temperatures rise, marine organisms are shifting toward the poles at a rate of over 60km per decade to

4 Jul 2026 · 25 min
Why Weight Loss Drugs Don't Work On Their Own Dr. Nick Fuller (480)

I'm joined by Dr Nick Fuller to dissect the long-term effectiveness of weight loss medications and why lasting results do actually require more than medication alone. Nick explains why evidence-based behavioural weight management programs remain the first-line approach to weight loss built on three key pillars: diet, exercise and sleep (did you even know that sleep plays a big role in regulating h

27 Jun 2026 · 24 min
Inside Microsoft's Global Research Lab With Dr. Peter Lee (479)

This episode I'm joined by Dr Peter Lee, Head of Research at Microsoft, to explore the ideas shaping the future of technology. Leading 14 research laboratories globally and overseeing a research and development program that receives more than 10% of Microsoft's overall budget, Dr Lee shares his journey to the top of one of the world's largest innovation engines. From AI tools transforming early ca

20 Jun 2026 · 34 min
The (Not So) Boring Billion with Prof. Dietmar Müller (478)

In this episode, we speak with Dietmar Müller about the "Boring Billion", a seemingly quiet period in Earth's deep history that may have been crucial for the evolution of complex life. Drawing on his latest research, Müller explains how plate tectonics, passive continental margins, and volcanic outgassing shaped Earth's slow carbon cycle and gradually oxygenated the oceans during the mid-Proterozo

13 Jun 2026 · 28 min
Solving a Cosmic Radio Signal Mystery with Kovi Rose (477)

Astronomer and soon-to-be Dr. Kovi Rose joins us to discuss his newly published Nature Astronomy paper on one of the universe's newest mysteries: strange repeating flashes of radio waves and X-rays coming form deep within our galaxy! His team's discovery of ASKAP J174 has helped identify the source as a pair of stars orbiting each other, with a white dwarf pulling or accreting material from its co

6 Jun 2026 · 29 min
Coffee & Blood Pressure Explained with Prof. Clare Collins (476)

Professor Clare Collins returns to the pod to answer a common question: does coffee raise your blood pressure? We also discuss how genetics influence whether you're a fast or slow caffeine metaboliser, the beneficial phytonutrients found in coffee, why decaf still has health benefits, and when people with high blood pressure may need to be more cautious with their intake. nomoneynotime.com.au

30 May 2026 · 17 min
The Hidden Health Benefits of Honey with Prof. Clare Collins (475)

Friend of the pod Professor Clare Collins returns to dive down into the sticky depths of the surprisingly powerful world of honey - far beyond being "just a sugary liquid". From the hallucinogenic "mad honey" of the Rhododendrons to the science behind medical-grade honey dressings that can heal wounds days faster than conventional treatments, Dr. Clare explains why this ancient food deserves a sec

23 May 2026 · 30 min
The Hunt for Dark Matter with Dr. Theresa Fruth (474)

What is the universe actually made of? Particle physicist Theresa Fruth join us at Shirtloads to explore one of science's greatest unsolved mysteries - dark matter! Making up roughly 85% of the universe, yet appearing in none of our known particles, dark matter is invisible, elusive and almost certainly the reason the universe (and us!) exist at all. Theresa and her team are hunting for it anyway.

16 May 2026 · 28 min